GMP Recombinant Human Interleukin-4
(rHuIL-4)

Description:

Recombinant Human IL-4 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 130 amino acids and having a molecular mass of 15000 Dalton. The rHuIL-4 is purified by proprietary chromatographic techniques.
 
Molecular weight: 15 KDa
Identity: rh IL-4 as measured by Elisa and Western Blot
Specific activity: > 13.10 6 units/mg compared to NIBSC standard . CT-h4.S cell proliferation assay.
650 000 IU /vial

Purity: > 98% as determined by SDS-PAGE and HPLC
Endotoxin content: < 0.1 EU/ µg of IL-4 (LAL test)
Host DNA: < 10 pg/ng protein
Sterility: sterile according to EP Test 2.6.1.
Stabiliser: contains Trehalose ; no preservative.
Physical state: freeze-dried
Stability: 12 months at – 20°C to – 80°C
3 months after reconstitution with water for injection ( as defined in EP Monograph 0169) when stored at -80°C
Reconstitution: use 500 µL water for injection in class A environment in order to keep the GMP grade .
Packaging unit: 50 µg protein (Lowry test)
 
GENTAUR rh IL-4 is manufactured in full compliance with cGMP in facilities approved by the Belgian Ministry of Health for the production and storage of medicinal products.

Use:
 
GENTAUR rh IL-4 is not an approved medicinal product and cannot be injected as such to patients.
FOR EX VIVO CELL CULTURE AND FOR IN VITRO RESEARCH USE ONLY
 

Cytokines with high activity for dendritic cell research:

rh: recombinant – human, rm: recombinant - mouse,  Net-prices in EURO,    for research only!  

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